CYFRA 21-1 as a tumour marker for bronchogenic carcinoma

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CYFRA 21-1 as a tumour marker for bronchogenic carcinoma.

Despite extensive research, the role of the commonly employed tumour markers in the diagnosis of lung carcinoma is yet to be clarified. The utility of a new marker, CYFRA 21-1, in the preoperative evaluation of patients with bronchogenic carcinoma was investigated. CYFRA 21-1 was determined with a radiometric assay in serum of 280 patients with lung cancer and 208 patients with various nonmalig...

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CYFRA 21-1 in urine: a diagnostic marker for endometriosis?

Diagnostic workup of endometriosis usually involves laparoscopic inspection and histological examination of biopsies. Unequivocal laboratory parameters for this ailment have not been available in routine diagnostic evaluations thus far. In this study, we examined urine concentrations of cytokeratin 19 (CYFRA 21-1), a structural protein specific for epithelia. We performed immunoassays for CYFRA...

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Cyfra 21-1 as a serum tumor marker for follow-up of patients with laryngeal and hypopharyngeal squamous cell carcinoma.

AIM To evaluate the importance and potential of Cyfra21-1 as a tumor marker (TM) for follow-up of patients with squamous cell carcinoma (SCC) in laryngeal and hypopharyngeal cancer. PATIENTS AND METHODS Cyfra21-1 serum levels of 50 patients with laryngeal and hypopharyngeal SCC were evaluated by ECLIA assay. Statistical analysis was performed using Kruskal-Wallis and Jonckheere-Terpstra tests...

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Editorials: elevated plasma calcitonin as a marker for bronchogenic carcinoma.

he observation of ectopic synthesis and secretion polypeptide hormones by nonendo, tumors has been reported with increasing frequency in the past decade. Carcinomas of the lung have been particularly versatile in this regard. Reports have included corticotropin ( adrenocorticotropic hormone) and vasopressin found in some oat-cell carcinomas, gonadotropins predominantly in large-cell carcinomas,...

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Cyfra 21 - 1 : an Overview

Cytokeratins are group of intermediate filament proteins and based on the tissue expression, cytokeratins are classified into simple epithelial cytokeratin and stratified epithelial cytokeratins. CK expression pattern in the malignant cells are usually retained from the cell of origin, and therefore CK are being used in tumor typing. Cyfra 21-1 is a soluble fragment of cytokeratin 19 is an acid...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 1995

ISSN: 0000-0000,0903-1936

DOI: 10.1183/09031936.95.08030407